Laryngopharyngeal reflux (LPR) is similar to another condition – GERD – that results from the contents of the stomach backing up (reflux). The most powerful of these medications are called Proton Pump Inhibitors (PPIs) and include Nexium, Prilosec, Prevacid, Dexilant and others. Usually, they must be taken for life but under the care of a knowledgeable physician, this GERD treatment can provide click to investigate acceptable relief for most GERD patients. There are short-term side effects such as headache, diarrhea and abdominal pain and over the long term they may increase the risk of hip fractures, cause low magnesium levels in the blood and increase the risk of pneumonia’s and a severe type of colon infection. It is easy to see why the proper supervision of a qualified physician is needed.
Gastroesophageal reflux (GER) is the term used to describe retrograde movement of gastric contents into the esophagus. Within certain limits, this is considered to be physiological, although a physiological relevance has yet to be established. The condition is named GER disease (GERD) when patients experience symptoms or when reflux results in esophageal damage (eg, esophagitis). There is no doubt that acid is the major aggressive component of the refluxate. GERD is a major burden to western societies and it was a major breakthrough when omeprazole – the first proton pump inhibitor (PPI) – was marketed in 1989. Since then, the acid component of GERD can be sufficiently treated; PPIs are the gold standard treatment for patients with GERD ( 1 ).
Non-erosive reflux disease (NERD) is the most common presentation of gastroesophageal reflux disease. Although acid reflux is the most important cause of symptom generation in NERD patients, non-acid reflux is also associated with reflux symptoms. The temporal relation between symptoms and reflux episodes is of importance in evaluating the results of combined pH-impedance monitoring in NERD patients. Mucosal hypersensitivity and mechanical stimulation due to great volume of non-acid reflux are among the putative mechanisms of symptom generation.
GERD is diagnosed clinically according to the typical symptoms that respond to treatment with a PPI or by 24 h esophageal pH monitoring, in which a pH below 4.0 is regarded to indicate acid reflux, and the length of time in which esophageal mucosa is in contact with acid is used to diagnose GERD. On the other hand, pH monitoring is not helpful in diagnosing nonacid reflux because it monitors acidity as an indirect marker of reflux but not the actual reflux. Therefore, in a patient not responding to PPI treatment, pH monitoring is helpful in identifying individuals who still produce acid while being on a standard or double dose of a PPI, but in whom pH monitoring is not helpful to measure nonacid reflux episodes.
In terms of heartburn, I have found that people of all ages suffer from this. I help out at the local high school to assist in coaching track and it’s amazing how many young people have heartburn and are on PPI’s. I Thought this was more of an elderly condition, but it’s not anymore. I’m starting to think this is more of a problem with how we eat nowdays. Our bodies just can’t handle the acidic american diet’s nowdays and as a result of it has been slowly breaking down to the point where our LES relaxes too much.