Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux , ulcers). 2. Combined results for Omeprazole Delayed-Release Capsules + clarithromycin, Omeprazole Delayed-Release Capsules, and clarithromycin treatment arms. St. John’s Wort, rifampin: Avoid concomitant use with Omeprazole Delayed-Release Capsules see Warnings and Precautions ( 5.9 ). Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine. -If there is a recurrence of erosive esophagitis (EE) or gastroesophageal reflux disease (GERD) symptoms, an additional 4 to 8-week course of treatment should be considered.
Bone fractures. People who take multiple daily doses of PPI medicines for a long period of time (a year or longer) may have an increased risk of fractures of the hip, wrist, or spine. You should take Omeprazole Delayed-Release Capsules exactly as prescribed, at the lowest dose possible for your treatment and for the shortest time needed. Talk to your doctor about your risk of bone fracture if you take Omeprazole Delayed-Release Capsules. Voriconazole: Dose adjustment of Omeprazole Delayed-Release Capsules is not normally required. However, in patients with Zollinger-Ellison syndrome, who may require higher doses, dose adjustment may be considered.
Serum chromogranin A (CgA) levels increase secondary to PPI-induced decreases in gastric acidity. The increased CgA level may cause false positive results in diagnostic investigations for neuroendocrine tumors see Warnings and Precautions ( 5.10 ), Clinical Pharmacology ( experienced 12.2 ). Keep the container of Omeprazole Delayed-Release Capsules dry and away from light. Omeprazole increases the concentration of cilostazol ( Pletal ). The dose of cilostazol should be reduced from 100 mg twice daily to 50 mg twice daily when given with omeprazole.
Omeprazole can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine. Several studies have reported no apparent adverse short-term effects on the infant when single dose oral or intravenous Omeprazole was administered to over 200 pregnant women as premedication for cesarean section under general anesthesia. Increased INR and prothrombin time in patients receiving PPIs, including Omeprazole, and warfarin concomitantly. Increases in INR and prothrombin time may lead to abnormal bleeding and even death.
Proton pump inhibitors (PPIs), including Omeprazole Delayed-Release Capsules, are contraindicated in patients receiving rilpivirine-containing products see Drug Interactions ( 7 ). Omeprazole Delayed-Release Capsules is indicated for short-term treatment (4 to 8 weeks) of active benign gastric ulcer in adults. Comment: If patients are not fully healed after 4 weeks, treatment may continue for another 4 weeks. Prilosec OTC is used for treating heartburn for up to two weeks, and the usual dose is 20 mg daily.