Uses, Side Effects, Interactions, Dosage, And Warning

Gastroesophageal reflux disease is a condition in which the contents of the stomach return to the food pipe or esophagus and impairs quality of life. Van Dau N, Ngoc Ham N, Huy Khac D, and et al. The effects of a traditional drug, tumeric (Curcuma longa), and placebo on the healing of duodenal ulcer. Phytomed 1998;5(1):29-34. Cashman, J. R., Ghirmai, S., Abel, K. J., and Fiala, M. Immune defects in Alzheimer’s disease: new medications development. BMC.Neurosci. 2008;9 Suppl 2:S13. View abstract. Khajehdehi, P., Zanjaninejad, B., Aflaki, E., Nazarinia, M., Azad, F., Malekmakan, L., and Dehghanzadeh, G. R. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr 2012;22(1):50-57. View abstract.

Sharma, R. A., Euden, S. A., Platton, S. L., Cooke, D. N., Shafayat, A., Hewitt, H. R., Marczylo, T. H., Morgan, B., Hemingway, D., Plummer, S. M., Pirmohamed, M., Gescher, A. J., and Steward, W. P. Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance. Clin Cancer Res 10-15-2004;10(20):6847-6854. View abstract. Mrudula, T., Suryanarayana, P., Srinivas, P. N., and Reddy, G. B. Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Commun. 9-21-2007;361(2):528-532. View abstract.

Nishiyama, T., Mae, T., Kishida, H., Tsukagawa, M., Mimaki, Y., Kuroda, M., Sashida, Y., Takahashi, K., Kawada, T., Nakagawa, K., and Kitahara, M. Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice. J Chem. 2-23-2005;53(4):959-963. View abstract. Shu, J. C., He, Y. J., Lv, X., Ye, G. R., and Wang, L. X. Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells. J 2009;63(4):415-420. View abstract.

Lamb, S. R. and Wilkinson, S. M. Contact allergy to tetrahydrocurcumin. Contact Dermatitis 2003;48(4):227. View abstract. Yu, Y. M. and Lin, H. C. Curcumin prevents human aortic smooth muscle cells migration by inhibiting of MMP-9 expression. Nutr.Metab 2010;20(2):125-132. View abstract. Azuine, M. A. and Bhide, S. V. Chemopreventive hop over to these guys effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr.Cancer 1992;17(1):77-83. View abstract. Curcumin inhibits the activity of nuclear factor kappa B and prevents activation of esophageal cells in response to low pH, thus reducing esophageal inflammation in GERD.

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